Fedratinib (hydrochloride hydrate), CAS [[1374744-69-0]]

Product Overview

• Article Name: Fedratinib (hydrochloride hydrate), CAS [[1374744-69-0]]
• Biozol Catalog Number: MCE-HY-10409A
• Supplier Catalog Number: HY-10409A
• Alternative Catalog Number: MCE-HY-10409A-2G,MCE-HY-10409A-10MG,MCE-HY-10409A-5G,MCE-HY-10409A-10MMX1ML,MCE-HY-10409A-500MG,MCE-HY-10409A-200MG,MCE-HY-10409A-100MG,MCE-HY-10409A-1G,MCE-HY-10409A-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: TG-101348 (hydrochloride hydrate), SAR 302503 (hydrochloride hydrate)

Product Description

Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].

Product Properties

• Molecular Weight: 615.62
• Purity: 99.92
• CAS Number: [1374744-69-0]
• Formula: C27H40Cl2N6O4S
• Target: Apoptosis,JAK

Application Notes

• Application Notes: MCE Product type: Reference compound