TG-101348 (hydrochloride hydrate) (Standard), SAR 302503 (hydrochloride hydrate) (Standard)
Fedratinib (hydrochloride hydrate) (Standard) is the analytical standard of Fedratinib (hydrochloride hydrate). This product is intended for research and analytical applications. Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].
Molecular Weight:
615.62
CAS Number:
[1374744-69-0]
Formula:
C27H40Cl2N6O4S
Target:
Apoptosis,JAK,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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