Fedratinib (Standard) is the analytical standard of Fedratinib. This product is intended for research and analytical applications. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].
Molecular Weight:
524.68
CAS Number:
[936091-26-8]
Formula:
C27H36N6O3S
Target:
Apoptosis,JAK,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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