Fedratinib-d9 (TG-101348-d9) is deuterium labeled Fedratinib. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2][3].
Molecular Weight:
533.73
Formula:
C27H27D9N6O3S
Target:
Apoptosis,Isotope-Labeled Compounds,JAK
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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