SB-431542 is a TGF-beta receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 µM, 0.75 µM and 2 µM, respectively. SB-431542 also inhibits TGF-beta-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways[1][2][3].
Molecular Weight:
384.39
Purity:
99.85
CAS Number:
[301836-41-9]
Formula:
C22H16N4O3
Target:
Apoptosis,Organoid,TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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