HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX[1].
Molecular Weight:
381.37
Purity:
99.42
CAS Number:
[1033836-12-2]
Formula:
C19H19F4N3O
Target:
PGE synthase
Application Notes:
MCE Product type: Reference compound
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