Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is a BBB-permeable and orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 µM and 1.4 µM, respectively[1][2].
Molecular Weight:
421.30
CAS Number:
[879085-55-9]
Formula:
C19H14Cl2N2O3S
Target:
Autophagy,Hedgehog,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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