Lexibulin (CYT-997) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines, with potent cytotoxic and vascular disrupting activity in vitro and in vivo[1][2]. Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells[3].
Molecular Weight:
434.53
Purity:
99.10
CAS Number:
[917111-44-5]
Formula:
C24H30N6O2
Target:
Apoptosis,Microtubule/Tubulin,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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