PH-064 (BIM-46187) is an orally active inhibitor of the heterotrimeric G-protein complex. PH-064 inhibits SERT activity and attenuates shear stress-induced Akt phosphorylation. PH-064 has potent anti-hyperalgesia activity. PH-064 inhibits G protein-coupled receptor-dependent tumorigenesis. PH-064 can be used in the study of pain (e.g., inflammatory pain, neuropathic pain), GPCR-dependent tumors, and inflammatory lung injury[1][2][3][4][5][6].
Molecular Weight:
795.11
Purity:
99.88
CAS Number:
[892546-37-1]
Formula:
C44H58N8O2S2
Target:
Akt,Serotonin Transporter
Application Notes:
MCE Product type: Reference compound
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