Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABAA) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC50 of 10 nM for recombinant alpha1beta1gamma2. Anticonvulsant effects[1][2][3].
Molecular Weight:
418.28
Purity:
99.13
CAS Number:
[84379-13-5]
Formula:
C19H20BrN3O3
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted