Rifalazil (KRM-1648, ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the beta-subunit in RNA polymerase[1]. Rifalazil (KRM-1648, ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 µg/ml[3]. Rifalazil (KRM-1648, ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2].
Molecular Weight:
941.07
Purity:
99.64
CAS Number:
[129791-92-0]
Formula:
C51H64N4O13
Target:
Antibiotic,Bacterial,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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