Abecarnil (ZK 112119) is a ligand or a partial agonist for benzodiazepine (BZ) receptor. Abecarnil possesses anxiolytic and anticonvulsant properties. Abecarnil can act as a positive allosteric modulator of GABAA receptor. Abecarnil inhibits the binding of the BZ [3H]lormetazepam to rat cerebral cortex membranes, with an IC50 of 0.82 nM. Abecarnil can be used for epilepsy research[1][2][3][4].
Molecular Weight:
404.46
Purity:
99.38
CAS Number:
[111841-85-1]
Formula:
C24H24N2O4
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
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