BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKepsilon, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCdelta, and GSK3beta, and has lower selectivity over PKA, PKC, c-Kit, GSK3beta etc. BX795 modulates autophagy[1][2][3][4].
Molecular Weight:
591.47
Purity:
99.84
CAS Number:
[702675-74-9]
Formula:
C23H26IN7O2S
Target:
Autophagy,IKK,PDK-1
Application Notes:
MCE Product type: Reference compound
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