Kahalalide F, CAS [[149204-42-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-105141
Supplier Catalog Number:
HY-105141
Alternative Catalog Number:
MCE-HY-105141-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Kahalalide F is a novel antitumor agent of marine origin. Kahalalide F can inhibit DNA synthesis. Kahalalide F cytotoxicity did not correlate with the expression level of the multidrug resistance MDR1 and of the tyrosine kinase HER2/NEU, and only slightly by the anti-apoptotic BCL-2 protein. Kahalalide F inhibits the PI3K-Akt signaling pathway by depleting ErbB3. Kahalalide F action was triggered rapidly by short pulse treatments. Kahalalide F induces cell death via oncosis preferentially in tumor cells. Kahalalide F can be used for the study of prostate cancer, breast cancer, vulval cancer, and non-small cell lung cancer[1][2][3].
Molecular Weight:
1477.87
CAS Number:
[149204-42-2]
Formula:
C75H124N14O16
Target:
Akt,DNA/RNA Synthesis,EGFR,PI3K
Application Notes:
MCE Product type: Peptides
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