(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk-1/KDR, PDGFRbeta, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 µM, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors[1][2].
Molecular Weight:
310.35
Purity:
99.44
CAS Number:
[210644-62-5]
Formula:
C18H18N2O3
Target:
FGFR,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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