CGS25155 is an orally active neutral endopeptidase 24.11 (NEP 24.11) inhibitor with an IC50 of 3 nM. CGS25155 can slow down the degradation of the cardiac hormone atrial natriuretic peptide (ANP) and exhibits antihypertensive activity in the DOCA-salt induced rat hypertension model. CGS25155 can be used in cardiovascular disease research[1].
Molecular Weight:
490.61
CAS Number:
[150126-87-7]
Formula:
C25H34N2O6S
Target:
Neprilysin
Application Notes:
MCE Product type: Reference compound
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