KF-17625 is an orally active bronchodilator. KF-17625 can inhibit bronchoconstriction induced by Carbachol (HY-B1208), Histamine (HY-B1204), or Leukotriene D4 (HY-113456). KF-17625 can inhibit canine tracheal phosphodiesterase (PDE) IV (IC50 = 12 µM) and Concanavalin-A (HY-P2149)-induced histamine release from rat mast cells (44% inhibition at 10 mM). KF-17625 can be used for the researches of immunology and inflammation[1].
Molecular Weight:
262.27
CAS Number:
[139339-02-9]
Formula:
C15H10N4O
Target:
Histamine Receptor,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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