Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation[1][2][3].
Molecular Weight:
460.97
Purity:
99.78
CAS Number:
[854107-55-4]
Formula:
C23H25ClN2O4S
Target:
LPL Receptor
Application Notes:
MCE Product type: Reference compound
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