MK-5596 is an efficient, selective and orally active CB1R (IC50 = 1.0 nM, EC50 = 5.8 nM) inverse agonist. MK-5596 has weak hERG inhibitory activity. MK-5596 has strong weight loss and appetite suppression effects. MK-5596 has a certain inhibitory effect on CYP enzymes (CYP3A4: IC50 = 3.3 µM, CYP2C8: IC50 = 11 µM, CYP2C9: IC50 = 18 µM, CYP2D6: IC50 = 6 µM). MK-5596 can be used for research on conditions such as obesity[1].
Molecular Weight:
541.86
CAS Number:
[1044586-68-6]
Formula:
C27H23Cl3N4O2
Target:
Cannabinoid Receptor,Cytochrome P450
Application Notes:
MCE Product type: Reference compound1
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