AVN-211 (CD-008-0173) is a selective and orally active 5HT6R antagonist with an IC50 of 2.34 nM and a Ki of 1.09 nM. AVN-211 exhibits 5K-fold higher 5HT6R selectivity over other 65 receptors, enzymes, and ion channels. AVN-211 significantly improves cognitive and anxiety behaviors in various AD animal models, and has good safety profiles. AVN-211 can be used for the study of Alzheimers dementia[1].
Molecular Weight:
333.43
CAS Number:
[1173103-84-8]
Formula:
C15H15N3O2S2
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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