MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent[1].
Molecular Weight:
393.38
Purity:
98.85
CAS Number:
[1314883-11-8]
Formula:
C18H14F3N3O2S
Target:
Parasite,PI4K
Application Notes:
MCE Product type: Reference compound
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