FK 973 is a dihydrobenzoxazine anticancer agent. FK 973 selectively inhibits DNA synthesis and can form DNA cross-links through cytoplasmic activation. FK 973 exhibits significant antitumor activity in various animal tumor models and human tumor xenografts, with relatively weak myelosuppressive effects. FK 973 is sensitive to neural tumor cells. FK 973 can be used for DNA-targeted antitumor research[1][2].
Molecular Weight:
447.40
CAS Number:
[114580-45-9]
Formula:
C20H21N3O9
Target:
DNA Alkylator/Crosslinker,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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