Izonsteride (Compound LY320236) is an inhibitor of 5alpha-reductase (IC50 = 11.6 nM for type I, 7.37 nM for type II). LY320236 inhibits the activity of steroid 5alpha-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity[1].
Molecular Weight:
422.61
CAS Number:
[176975-26-1]
Formula:
C24H26N2OS2
Target:
5 alpha Reductase
Application Notes:
MCE Product type: Reference compound
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