Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
Molecular Weight:
356.85
Purity:
99.41
CAS Number:
[1038915-64-8]
Formula:
C19H21ClN4O
Target:
Apoptosis,PARP
Application Notes:
MCE Product type: Reference compound
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