Crinecerfont (hydrochloride), CAS [[321839-75-2]]

Product Overview

• Article Name: Crinecerfont (hydrochloride), CAS [[321839-75-2]]
• Biozol Catalog Number: MCE-HY-106203A
• Supplier Catalog Number: HY-106203A
• Alternative Catalog Number: MCE-HY-106203A-25MG,MCE-HY-106203A-5MG,MCE-HY-106203A-50MG,MCE-HY-106203A-100MG,MCE-HY-106203A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: SSR-125543 (hydrochloride)

Product Description

Crinecerfont (SSR-125543) hydrochloride is an orally effective corticotropin-releasing factor receptor type-1 (CRF1 receptor) antagonist. Crinecerfont hydrochloride blocks CRF1 receptor signaling to reduce adrenocorticotropic hormone secretion. Crinecerfont hydrochloride improves hypothalamic-pituitary-adrenal axis negative feedback sensitivity in chronically stressed mice. Crinecerfont hydrochloride can be used for the research of chronic stress conditions and classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency[1][2]. Crinecerfont hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Properties

• Molecular Weight: 519.50
• Purity: 98.82
• CAS Number: [321839-75-2]
• Formula: C27H29Cl2FN2OS
• Target: CFTR

Application Notes

• Application Notes: MCE Product type: Reference compound