Crinecerfont (tosylate), CAS [[2649012-17-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-106203C
Supplier Catalog Number:
HY-106203C
Alternative Catalog Number:
MCE-HY-106203C-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
SSR-125543 (tosylate)
Crinecerfont (SSR-125543) tosylate is an orally effective corticotropin-releasing factor receptor type-1 (CRF1 receptor) antagonist. Crinecerfont tosylate blocks CRF1 receptor signaling to reduce adrenocorticotropic hormone secretion. Crinecerfont tosylate improves hypothalamic-pituitary-adrenal axis negative feedback sensitivity in chronically stressed mice. Crinecerfont tosylate can be used for the research of chronic stress conditions and classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency[1][2]. Crinecerfont tosylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
655.24
CAS Number:
[2649012-17-7]
Formula:
C34H36ClFN2O4S2
Target:
CFTR
Application Notes:
MCE Product type: Reference compound
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