Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation[1][2].
Molecular Weight:
617.65
Purity:
99.81
CAS Number:
[355151-12-1]
Formula:
C28H39N7O9
Target:
Connexin,Gap Junction Protein
Application Notes:
MCE Product type: Reference compound
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