SB 247083 is a selective, competitive and orally active endothelin-A receptor antagonist with a Ki of 0.41 nM. SB 247083 shows a Ki of 467 nM to endothelin-B receptor. SB 247083 shows a Kb of 3.5 nM for ET-1-induced contraction of rat aorta. SB 247083 can be used for the research of cardiovascular disease[1].
Molecular Weight:
617.09
CAS Number:
[188186-61-0]
Formula:
C34H33ClN2O7
Target:
Endothelin Receptor
Application Notes:
MCE Product type: Reference compound1
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