ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin FKBP52 and to the beta1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for FKBP52 versus FKBP12[1].
Molecular Weight:
1023.30
CAS Number:
[892494-07-4]
Formula:
C57H86N2O14
Target:
Calcium Channel,FKBP
Application Notes:
Reference compound
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