Adrenocorticotropic hormone (ACTH, Adrenocorticotrophic hormone) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone TFA stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone TFA regulates cortisol and androgen production. Adrenocorticotropic hormone TFA can promote the development of spermatogenesis. Adrenocorticotropic hormone TFA can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone TFA can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome[1][2][3][4].
Molecular Weight:
4541.14 (free base)
Purity:
99.85
Formula:
C207H308N56O58S.xC2HF3O2
Target:
Androgen Receptor,Interleukin Related,Mitochondrial Metabolism,Reactive Oxygen Species (ROS),TNF Receptor
Application Notes:
MCE Product type: Reference compound
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