L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 µM, 8.6 µM, and 29 µM, respectively.
Molecular Weight:
222.31
Purity:
99.35
CAS Number:
[83730-53-4]
Formula:
C8H18N2O3S
Target:
Ferroptosis
Application Notes:
Reference compound
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