L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 µM, 8.6 µM, and 29 µM, respectively[1][2].
Molecular Weight:
258.77
Purity:
98.39
Formula:
C8H19ClN2O3S
Target:
Ferroptosis
Application Notes:
Reference compound
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