Arimoclomol (BRX-220 free base) is an orally active co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.Arimoclomol can be used for the study of Niemann-Pick disease type C. Arimoclomol can cross the blood-brain barrier and can be used in research on Niemann-Pick disease type C[1][2][3].
Molecular Weight:
313.78
Purity:
99.83
CAS Number:
[289893-25-0]
Formula:
C14H20ClN3O3
Target:
HSP
Application Notes:
MCE Product type: Reference compound
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