Sulofenur (Diarylsulfonylurea, LY186641) is an orally active anti-tumor agent. Sulofenur induces gene expression through calcium ion-dependent pathways and some protein kinase-independent pathways, and its effect is particularly enhanced in H-ras mutant cells. Sulofenur exhibits significant activity in mouse solid tumor models and human tumor xenograft models[1][2][3].
Molecular Weight:
350.82
CAS Number:
[110311-27-8]
Formula:
C16H15ClN2O3S
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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