Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by kappa-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research[1][2].
Molecular Weight:
330.42
CAS Number:
[61325-80-2]
Formula:
C17H19FN4S
Target:
5-HT Receptor,Dopamine Receptor
Application Notes:
MCE Product type: Reference compound
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