Oxodipine, a dihydropyridine-type calcium antagonist, inhibits KCl-induced aortic contraction in rabbits and reduces cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduces L-type Ca currents (I) with an IC50 of 0.24 µM, and against T-type Ca currents (I) with an IC50 of 0.41 µM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs[1][2][3][4][5][6].
Molecular Weight:
359.37
CAS Number:
[90729-41-2]
Formula:
C19H21NO6
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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