3'-Azido-2',3'-dideoxyuridine (AzdU) is a nucleoside analog of Zidovudine (HY-17413). 3'-Azido-2',3'-dideoxyuridine is a potent inhibitor of human immunodeficiency virus (HIV) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC)[1][2][3]. 3'-Azido-2',3'-dideoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
253.21
Purity:
99.59
CAS Number:
[84472-85-5]
Formula:
C9H11N5O4
Target:
HIV
Application Notes:
MCE Product type: Reference compound1
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