SG-210 (SPR 210) is an orally active and selective aldose reductase (AR) inhibitor. SG-210 has IC50 values of 9.5 nM and 10 nM for AR from porcine lens and human placenta, respectively. SG-210 can inhibit sorbitol accumulation and ameliorate diabetic neuropathy and retinopathy in Streptozotocin (HY-13753)-induced diabetic rats. SG-210 can be used in the research of diseases such as diabetes-related complications[1].
Molecular Weight:
424.42
CAS Number:
[143162-65-6]
Formula:
C18H11F3N2O3S2
Target:
Aldose Reductase
Application Notes:
MCE Product type: Reference compound
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