Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research[1][2][3][4].
Molecular Weight:
241.25
Purity:
98.06
CAS Number:
[133432-71-0]
Formula:
C12H11N5O
Target:
HIV,Nucleoside Antimetabolite/Analog
Application Notes:
MCE Product type: Reference compound
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