Ezlopitant (CJ-11,974) is a selective, non-peptidic neurokinin-1 (NK-1)-receptor antagonist. Ezlopitant inhibits both acute and delayed emetic reactions induced by Cisplatin (HY-17394) in ferrets via acting on NK1 receptors in the central nervous system. Ezlopitant has the potential for pain, chemotherapy-induced emesis and irritable bowel syndrome research[1][2][3].
Molecular Weight:
454.65
CAS Number:
[147116-64-1]
Formula:
C31H38N2O
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound1
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