Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule and anti-inflammatory agent. Aspartyl-alanyl-diketopiperazine increases the level of active Rap1 in activated human T lymphocytes and reduces the phosphorylation levels of Ras, ATF-2, c-jun, MEK1, MEKK1, ERK1, JNK1,2,3, p38MAPK and MEF-2. Aspartyl-alanyl-diketopiperazine inhibits the production of pro-inflammatory cytokines, including the levels of IFN-gamma and TNF-alpha. Aspartyl-alanyl-diketopiperazine can be used in studies of inflammatory immune responses[1][2].
Molecular Weight:
186.17
Purity:
98.87
CAS Number:
[110954-19-3]
Formula:
C7H10N2O4
Target:
IFNAR,JNK,MEK,p38 MAPK,Ras,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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