Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma[1].
Molecular Weight:
357.80
Purity:
99.47
CAS Number:
[1227056-87-2]
Formula:
C18H19ClF3NO
Target:
Serotonin Transporter
Application Notes:
MCE Product type: Reference compound
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