NSC12 is an orally active pan-FGF trap. NSC12 inhibits the interaction between FGF2/FGFR. NSC12 suppresses the phosphorylation of FGFR3. NSC12 reduces c-Myc levels, induces DNA damage, triggers the cleavage of Caspase 3, and promotes ROS production. NSC12 exhibits anticancer activity against lung cancer and multiple myeloma[1][2].
Molecular Weight:
484.52
Purity:
99.27
CAS Number:
[102586-30-1]
Formula:
C24H34F6O3
Target:
Caspase,c-Myc,DNA/RNA Synthesis,FGFR,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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