NU6140 is a selective CDK2-cyclin A inhibitor (IC50, 0.41 µM), exhibits 10- to 36-fold selectivity over other CDKs[1]. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively[2]. Enhances the apoptotic effect, with anti-cancer activity[1][2].
Molecular Weight:
422.52
Purity:
99.07
CAS Number:
[444723-13-1]
Formula:
C23H30N6O2
Target:
Aurora Kinase,CDK
Application Notes:
MCE Product type: Reference compound
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