cis-MZ 1 hydrate is a negative control for BRD4-targeted PROTAC MZ 1 (HY-107425). cis-MZ 1 or MZ 1 is a combination of the von Hippel-Lindau ligand (red part in the structural formula) and the BRD4 ligand (blue part in the structural formula). The Kd of MZ 1 for BRD4 BD1/2 was 382 nM and 120 nM, respectively[1].
Molecular Weight:
1007.15
Purity:
99
Formula:
C49H60ClN9O8S2.1/4H2O
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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