PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP, exhibiting nanomolar potency against MMP-2, MMP-3 and MMP-13 (IC50=4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1, -7 and -9 (IC50=6.0, 7.2, and 7.9 µM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure[1][2][3].
Molecular Weight:
412.30
Purity:
99.21
CAS Number:
[199850-67-4]
Formula:
C17H18BrNO4S
Target:
MMP
Application Notes:
MCE Product type: Reference compound
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