Abrocitinib, CAS [[1622902-68-4]]

Product Overview

• Article Name: Abrocitinib, CAS [[1622902-68-4]]
• Biozol Catalog Number: MCE-HY-107429
• Supplier Catalog Number: HY-107429
• Alternative Catalog Number: MCE-HY-107429-10MG,MCE-HY-107429-100MG,MCE-HY-107429-50MG,MCE-HY-107429-5MG,MCE-HY-107429-25MG,MCE-HY-107429-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-04965842

Product Description

Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 µM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease[1].

Product Properties

• Molecular Weight: 323.41
• Purity: 99.26
• CAS Number: [1622902-68-4]
• Formula: C14H21N5O2S
• Target: JAK

Application Notes

• Application Notes: MCE Product type: Reference compound