SirReal1-O-propargyl, CAS [[1862237-99-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-107453
Supplier Catalog Number:
HY-107453
Alternative Catalog Number:
MCE-HY-107453-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
PROTAC Sirt2-binding moiety 1
SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 µM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2[1]. SirReal1-O-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
424.54
Purity:
93.77
CAS Number:
[1862237-99-7]
Formula:
C21H20N4O2S2
Target:
Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound
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