LDN-211904 oxalate is a potent and reversible EphB3 inhibitor with an IC50 of 79 nM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with Cetuximab (HY-P9905) could be effective in inhibiting STAT3-activated colorectal cancer (CRC) stemness and Cetuximab resistance in CRC[1][2].
Molecular Weight:
444.87
Purity:
99
CAS Number:
[1198408-78-4]
Formula:
C21H21ClN4O5
Target:
Ephrin Receptor
Application Notes:
MCE Product type: Reference compound
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