WK298 is a potent inhibitor of the MDM2/MDMX-p53 interaction with good anti-tumor activity. WK298 can fully activate the p53 pathway by inhibiting the binding of MDM2 and MDMX to p53. The development of WK298 benefited from a deep understanding of the key elements of the p53-MDM2/MDMX interaction structure[1].
Molecular Weight:
629.62
CAS Number:
[1067654-70-9]
Formula:
C35H38Cl2N6O
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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